Prior to this, LSU utilized the quarters of the Institute for the Deaf, Mute, and Blind.Land for the present campus was purchased in 1918, construction started in 1922, and the move began in 1925; however, it was not until 1932 that the move was finally completed.During the course of the war, the university reopened briefly in April 1863, but was closed once again with the invasion of the Red River Valley by the Union Army.

The current LSU main campus was dedicated in 1926, consists of more than 250 buildings constructed in the style of Italian Renaissance architect Andrea Palladio, and occupies a 650-acre (2.6 kmĀ²) plateau on the banks of the Mississippi River. Hebert Law Center, have received national recognition in their respective fields of study.

LSU is the flagship institution of the Louisiana State University System. Designated as a land-grant, sea-grant and space-grant institution, LSU is also noted for its extensive research facilities, operating some 800 sponsored research projects funded by agencies such as the National Institutes of Health, the National Science Foundation, the National Endowment for the Humanities, and the National Aeronautics and Space Administration.

Modeled initially after Virginia Military Institute, the institution opened with five professors and nineteen cadets on January 2, 1860, with Colonel William Tecumseh Sherman as superintendent.

The original location of the Old LSU Site is listed on the National Register of Historic Places.

In 1930, Huey Pierce Long, Jr., the governor, initiated a massive building program to expand the physical plant and add departments.

By 1936, LSU had the finest facilities in the South, a top-notch faculty of 394 professors, a new medical school, more than 6,000 students, and a winning football team.

Following the surrender of the Confederates at Appomattox Court House on April 9, 1865, General Sherman donated two cannons to the institution.

These cannons had been captured from Confederate forces after the close of the war and had been used during the initial firing upon Fort Sumter in April 1861.

This prompted the final name change for the university to the Louisiana State University and Agricultural & Mechanical College. She was admitted into a program to pursue a master's degree.

In 1905, LSU admitted its first female student, Miss R. The following year, 1906, LSU admitted sixteen female students to its freshman class as part of an experimental program. In 1907, LSU's first female graduate, Miss Martha Mc C. On April 30, 1926, the present LSU campus was formally dedicated, following the school's history at the federal garrison grounds (now the site of the state capitol) where it had been located since 1886.

The cannons are still displayed in front of LSU's Military Science/Aerospace Studies Building.